Taxol-induced microtubules from different sources: an ultrastructural comparison

J Submicrosc Cytol Pathol. 1988 Jul;20(3):613-7.

Abstract

Microtubules from different sources have been isolated using 20 microM taxol. An ultrastructural comparison allowed us to reveal some differences among taxol dependent structures. In tobacco pollen tubes a characteristic system of thin filaments was associated with taxol-induced microtubules. Similar filamentous complexes were not observed in taxol-induced microtubules isolated from other sources.

Publication types

  • Comparative Study

MeSH terms

  • Alkaloids / pharmacology*
  • Animals
  • Brain / drug effects
  • Brain / ultrastructure
  • Cell Line
  • Fibroblasts / drug effects
  • Fibroblasts / ultrastructure
  • Humans
  • Microtubules / drug effects
  • Microtubules / ultrastructure*
  • Nicotiana / ultrastructure
  • Paclitaxel
  • Plants, Toxic
  • Swine
  • Zea mays / ultrastructure

Substances

  • Alkaloids
  • Paclitaxel