Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017

Affiliations

• ¹ Ironwood Pharmaceuticals, Cambridge, MA 02142 USA
• ² Bayer AG, Drug Discovery - Cardiovascular Research, Wuppertal, Germany
• ³ Department of Cardiometabolic Diseases Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT USA
• ⁴ Department of Small Molecule Drug Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT USA
• ⁵ Department of Pharmacology, University of Oslo and Oslo University Hospital, Oslo, Norway
• ⁶ Institute of Experimental Medical Research, University of Oslo and Oslo University Hospital, Oslo, Norway
• ⁷ Center for Heart Failure Research, University of Oslo and Oslo University Hospital, Oslo, Norway
• ⁸ Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tuebingen, Tuebingen, Germany
• ⁹ Physiologisches Institut, Universität Würzburg, Würzburg, Germany
• ¹⁰ Molecular Cardiology Research Institute, Tufts Medical Center, Boston, Massachusetts 02111 USA
• ¹¹ Present Affiliation: Division of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania ,15224 USA
• ¹² Present Affiliation: Department of Medicine, Brown University School of Medicine, Providence, Rhode Island ,02912 USA
• ¹³ Division of Cardiology, Tufts Medical Center, Boston, Massachusetts 02111 USA
• ¹⁴ Max Planck Institute for Biophysical Chemistry, Göttingen and German Cancer Research Center (DKFZ), Heidelberg, Germany
• ¹⁵ Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 USA
• ¹⁶ Institut für Kardiogenetik and Universitäres Herzzentrum Lübeck, Universität zu Lübeck, Lübeck, Germany & DZHK e.V. (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Lübeck, Germany
• ¹⁷ Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, Munich, Germany
• ¹⁸ Center for Thrombosis & Hemostasis, Universitätsklinikum der Johannes Gutenberg-Universität Mainz, Mainz, Germany
• ¹⁹ Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V, Dortmund, Germany
• ²⁰ Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia
• ²¹ UCD Conway Institute, UCD School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
• ²² Division of Pulmonary, Sleep and Critical Care Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, RI USA
• ²³ Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, PA USA
• ²⁴ Institute of Cellular Medicine, Newcastle University, Newcastle, UK
• ²⁵ Center for Pulmonary Vascular Disease and Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, QC Canada
• ²⁶ Department of Cardiology, Erasme University Hospital, Brussels, Belgium
• ²⁷ Assistance Publique–Hôpitaux de Paris, Service de Pneumologie, Hôpital Bicêtre, Université Paris-Sud, Laboratoire d’Excellence en Recherche sur le Médicament et Innovation Thérapeutique, and INSERM Unité 999, Le Kremlin–Bicêtre, France
• ²⁸ Global Clinical Development, Bayer AG, Berlin, Germany
• ²⁹ Global Clinical Development, Bayer HealthCare Pharmaceuticals, Barcelona, Spain
• ³⁰ Chrestos Concept GmbH & Co, Essen, Germany
• ³¹ Clinic for Respiratory Medicine, Hannover Medical School, Hannover, Germany
• ³² Department of Biochemistry and Molecular Genetics, Hospital Clinic-University of Barcelona, Barcelona, Spain
• ³³ Department of Otolaryngology, Head and Neck Surgery, Hearing Research Centre Tübingen, Molecular Physiology of Hearing, University of Tübingen, Elfriede-Aulhorn-Straße 5, 72076 Tübingen, Germany
• ³⁴ Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe-Seyler-Straße 4, 72076 Tübingen, Germany
• ³⁵ Department of Pharmacology and Toxicology, University of Bochum, Universitätsstr 150, 44780 Bochum, Germany
• ³⁶ Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany
• ³⁷ Department of Physiology, University of Würzburg, Röntgenring 9, 97070 Würzburg, Germany
• ³⁸ Department of Biochemistry, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan
• ³⁹ Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
• ⁴⁰ Department of Regenerative Medicine and Tissue Engineering, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan
• ⁴¹ William Harvey Research Institute, Barts & The London School of Medicine, QMUL, London, UK
• ⁴² Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland USA
• ⁴³ Department of Experimental Medicine, University of Perugia, 06123 Perugia, Italy
• ⁴⁴ King’s College London, Cardiovascular Division, The Rayne Institute, St Thomas’ Hospital, London, UK
• ⁴⁵ Structural and Computational Biology and Molecular Biophysics Program, Baylor College of Medicine, Houston, TX USA
• ⁴⁶ Department of Pharmacology, Baylor College of Medicine, Houston, TX USA
• ⁴⁷ Department of Biochemistry, University of Kassel, Kassel, Hesse Germany
• ⁴⁸ Berkeley Center for Structural Biology, Lawrence Berkeley National Laboratory, Berkeley, CA USA
• ⁴⁹ Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX USA
• ⁵⁰ Technische Universität München, Department of Chemistry, Biomolecular NMR Spectroscopy, Garching, Germany
• ⁵¹ Technische Universität München, Department of Chemistry, Computational Biocatalysis, Garching, Germany
• ⁵² Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany
• ⁵³ Institute of Molecular Cell and Systems Biology, University of Glasgow, Glasgow, UK
• ⁵⁴ BHF Centre of Research Excellence, King’s College London, London, SE1 7EH UK
• ⁵⁵ Core Facility for Mouse Pathology, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany
• ⁵⁶ Faculty of Medicine, Department of Medicine, Imperial College London, London, SW7 2AZ UK
• ⁵⁷ Excellence Cluster Cardio-Pulmonary System, Universities of Giessen and Marburg Lung Centre Member of the German Lung Canter Justus-Liebig-University Giessen, Giessen, Germany
• ⁵⁸ Center for Integrated Protein Science Munich CiPSM at the Department of Pharmacy – Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany
• ⁵⁹ Institute for Ophthalmic Research, Centre for OphthalmologyUniversity of Tübingen, Tübingen, Germany
• ⁶⁰ University Eye Hospital, Centre for Ophthalmology Tübingen, University of Tübingen, Tübingen, Germany
• ⁶¹ STZ eyetrial at the Centre for Ophthalmology, University of Tübingen, Tübingen, Germany
• ⁶² Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD 21205 USA
• ⁶³ Heart Institute and Advanced Clinical Biosystems Research Institute, Cedar Sinai Medical Center, 8700 Beverly Blvd, AHSP A9229, Los Angeles, California 90048 USA
• ⁶⁴ McAllister Heart Institute, Division of Cardiology, UNC, Chapel Hill, NC USA
• ⁶⁵ Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056 USA
• ⁶⁶ Department of Pyhisology, Anatomy and GeneticsUniversity of Oxford, Oxford, UK
• ⁶⁷ Institute for Pharmacology and Toxicology, Medical Faculty, Ruhr-University Bochum, 44780 Bochum, Germany
• ⁶⁸ Department of Molecular Biology and Genetics - Molecular Cell and Developmental Biology, Aarhus University, C.F. Møllers Allé 3, 8000 Aarhus C, Denmark
• ⁶⁹ Institute of Experimental Cardiovascular Research, Center for Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
• ⁷⁰ Computational Biochemistry and Biophysics Laboratory (CBBL), U_ScienceTech (UST), University of Vic - Central University of Catalonia (UVIC-UCC), Vic, Barcelona Spain
• ⁷¹ Center for Heart Failure Research, University of Oslo, Oslo, Norway
• ⁷² Department of Physiology, Anatomy and Genetics, Oxford University, Oxford, UK
• ⁷³ German Center for Cardiovascular Research, University Medical Center Hamburg-Eppendorf and Institute of Experimental Cardiovascular Research, Hamburg, Germany
• ⁷⁴ Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
• ⁷⁵ Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Canada
• ⁷⁶ Department of Biochemistry and Molecular Medicine, George Washington University, School of Medicine, Washington, DC USA
• ⁷⁷ Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, Sao Paolo Brazil
• ⁷⁸ King’s College London, Cardiovascular Division, The British Heart Foundation Centre of Excellence, The Rayne Institute, St Thomas’ Hospital, London, SE1 7EH UK
• ⁷⁹ Department of Pharmacology, Baylor College of Medicine, Houston, Texas USA
• ⁸⁰ Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University, Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
• ⁸¹ DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
• ⁸² Department of Physiology, University of Lübeck, DZHK Partner Site Hamburg/Kiel/Lübeck, University Heart Centre Lübeck, Lübeck, Germany
• ⁸³ Interfakultäres Institut für Biochemie, University of Tübingen, Hoppe-Seyler-Str. 4, 72076 Tübingen, Germany
• ⁸⁴ King’s College London, Cardiovascular Division, British Heart Foundation Centre of Excellence, the Rayne Institute, St Thomas´ Hospital, SE17EH, London, UK
• ⁸⁵ Institute of Experimental Biomedicine II, University Medical Center Würzburg, Grombühlstraße 12, 97080 Würzburg, Germany
• ⁸⁶ Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
• ⁸⁷ Department of Chemistry, Wake Forest University, Winston-Salem, North Carolina 27109 USA
• ⁸⁸ Institute of Biochemistry and Pathobiochemistry - Microbial Biochemistry, Ruhr University Bochum, Universitätsstrasse 150, 44780 Bochum, Germany
• ⁸⁹ Interfakultäres Institut für Biochemie, University of Tübingen, Tübingen, Germany
• ⁹⁰ Interfakultäres Institut für Biochemie, Universität Tübingen, Tübingen, Germany
• ⁹¹ Institut für Physiologie, Universität zu Lübeck, Lübeck, Germany
• ⁹² Department of Cardiology & Cardiovascular Medicine, University of Tübingen, Tübingen, Germany
• ⁹³ Department of Biochemistry, University of Kassel, 34132 Kassel, Germany
• ⁹⁴ Department of Pharmacology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas USA
• ⁹⁵ Department of Internal Medicine, University of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany
• ⁹⁶ Centre for Pulmonary Hypertension at the Thoraxclinic of University Hospital Heidelberg, Heidelberg, Germany
• ⁹⁷ Department of Cardiology, Guangdong General Hospital and Guangdong Cardiovascular Institute, Guangzhou, Guangdong China
• ⁹⁸ Department of Cardiology and Angiology of the First Faculty of Medicine and General Teaching Hospital, Prague, Czech Republic
• ⁹⁹ State Key Laboratory of Cardiovascular Disease FuWai Hospital, National Center for Cardiovascular DiseasePeking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
• ¹⁰⁰ Discipline of Medicine, University of Tasmania, Hobart, Australia
• ¹⁰¹ Center for Pulmonary Vascular Disease, McGill University, Montreal, QC Canada
• ¹⁰² Department III of Internal Medicine and Cologne Cardiovascular Research Centre, Cologne University Heart Centre, Cologne, Germany
• ¹⁰³ Bayer HealthCare Pharmaceuticals, São Paulo, Brazil
• ¹⁰⁴ Global Clinical Development, Bayer AG, Wuppertal, Germany
• ¹⁰⁵ Université Paris-Sud, Université Paris-Saclay, Le Kremlin Bicêtre, France
• ¹⁰⁶ Department of Pharmacology and Toxicology, University of Regensburg, 93053 Regensburg, Germany
• ¹⁰⁷ Department Functional Genomics, University of Regensburg, 93053 Regensburg, Germany
• ¹⁰⁸ Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 8572 USA
• ¹⁰⁹ Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas USA
• ¹¹⁰ Geisinger Commonwealth School of Medicine, Commonwealth Medical College, Scranton, PA 18509 USA
• ¹¹¹ Department of Medicine, University of California, San Diego, La Jolla, California, USA
• ¹¹² Department of Pharmacology and Toxicology, University of Graz, A 8010, Graz, Austria
• ¹¹³ Department of Pharmacology and Toxicology, Ruhr University Bochum, D 44780 Bochum, Germany
• ¹¹⁴ Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka, 812-8581 Japan
• ¹¹⁵ Department of Biochemistry, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishiro-dai, Suita-City, Osaka 565-8565 Japan
• ¹¹⁶ Institute of Pharmaceutical Sciences, Department of Pharmacology and Toxicology, University of Graz, Graz, Austria
• ¹¹⁷ Institute of Molecular Biology and Biochemistry, Center of Molecular Medicine, Medical University of Graz, Graz, Austria
• ¹¹⁸ Department of Pharmacology and Toxicology, Ruhr University Bochum, Bochum, Germany
• ¹¹⁹ Department of Pharmacology, Faculty of Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway
• ¹²⁰ Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Oslo, Norway
• ¹²¹ Department of Biomedicine, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway
• ¹²² Advanced Telecommunications Research Institute International (ATR), The Thomas N. Sato BioMEC-X Laboratories, Kyoto, Japan
• ¹²³ The University of Tokyo, graduate school of frontier science, Kashiwa, Japan
• ¹²⁴ Max-Delbrück-Centrum für Molekulare Medizin, Berlin, Germany
• ¹²⁵ Present address: Interfakultäres Institut für Biochemie, University of Tübingen, Tübingen, Germany
• ¹²⁶ Present address: Institut für Zellbiologie des Nervensystems, München, TU Germany
• ¹²⁷ Present address: Institut für Immunologie, BioMedical Center, LMU, Planegg-Martinsried, Germany
• ¹²⁸ Laboratory for Optics and Biosciences, Ecole Polytechnique, Palaiseau, France
• ¹²⁹ Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN USA
• ¹³⁰ Department of Cell Biology, University of Connecticut Health Center, Farmington, CT USA
• ¹³¹ Department of Surgery, University of Minnesota, Minneapolis, MN USA
• ¹³² Department of Pharmacology, University of Minnesota, Minneapolis, MN USA
• ¹³³ Department of Developmental and Surgical Sciences, University of Minnesota, Minneapolis, MN USA
• ¹³⁴ Department of Physical Therapy, Georgia State University, Atlanta, GA USA
• ¹³⁵ Cardiovascular Research II, Therapeutic Research Group, Drug Discovery, Bayer AG, Wuppertal, Germany
• ¹³⁶ Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
• ¹³⁷ Heart and Vascular Center, Semmelweis University, Budapest, Hungary
• ¹³⁸ Humboldt Universität zu Berlin, Institute for Biology, Experimental Biophysics, Berlin, Germany
• ¹³⁹ University Medical Center Hamburg-Eppendorf, Center for Molecular Neurobiology Hamburg, Institute for Synaptic Physiology, Hamburg, Germany
• ¹⁴⁰ Center of Advanced European Studies and Research (caesar) Bonn, Department: Molecular Sensory Systems, Bonn, Germany
• ¹⁴¹ Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany
• ¹⁴² Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany
• ¹⁴³ Department of Biochemistry, University of Minnesota, Minneapolis, Minnesota USA
• ¹⁴⁴ Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut USA
• ¹⁴⁵ Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany
• ¹⁴⁶ Department of Myocardial Function, Imperial College London, Hammersmith Hospital, W12 0NN, London, England UK
• ¹⁴⁷ Institute of Physiology, Universität Würzburg, 97070 Würzburg, Germany
• ¹⁴⁸ Department of Pharmacology and Toxicology, University of Graz, A 8010 Graz, Austria
• ¹⁴⁹ Department of Medicine, University of California San Diego, La Jolla, California, 92093 USA
• ¹⁵⁰ Division of Medical Genetics and Cardiology, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, Texas 77030 USA
• ¹⁵¹ Department of Pharmacy, University of Patras, GR-26504 Patras, Greece
• ¹⁵² Institute of Organic Chemistry, Leipzig University, D-04103 Leipzig, Germany
• ¹⁵³ School of Health Sciences, Faculty of Pharmacy, University of Athens, GR-15 771 Athens, Greece
• ¹⁵⁴ Department of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195 USA
• ¹⁵⁵ Kansas State University, Manhattan, Kansas 66506 USA
• ¹⁵⁶ Decibel Therapeutics, Cambridge, MA 02142 USA
• ¹⁵⁷ Department for Pharmacology and Personalized Medicine, CARIM, FHML, Maastricht University, Maastricht, The Netherlands
• ¹⁵⁸ Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany
• ¹⁵⁹ Asklepios-Klinik Radeberg, Dresden, Germany
• ¹⁶⁰ Vesalius Research Center, Katholieke Universiteit Leuven, Leuven, Belgium
• ¹⁶¹ Residency Anaesthesiology, Department of Anaesthesiology und Critical Care Medicine, Technische Universität, Dresden, Germany
• ¹⁶² Facultad de Química, Universidad Autónoma de Querétaro, Santiago de Querétaro, Mexico
• ¹⁶³ Institut für Herz- und Kreislaufphysiologie Heinrich-Heine-Universität, Düsseldorf, Germany
• ¹⁶⁴ Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany
• ¹⁶⁵ Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University of Tübingen, Tübingen, Germany
• ¹⁶⁶ Centre for Integrative Physiology, School of Biomedical Science, Hugh Robson Building, University of Edinburgh, Edinburgh, Scotland EH8 9XD UK
• ¹⁶⁷ Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts USA
• ¹⁶⁸ Cardiovascular Research Center, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts USA
• ¹⁶⁹ Harvard Stem Cell Institute, Cambridge, Massachusetts USA
• ¹⁷⁰ Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts USA
• ¹⁷¹ Center for Genomic Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts USA
• ¹⁷² Division of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts USA
• ¹⁷³ Hematology Centre, School of Medical Sciences, University of Campinas (UNICAMP), Sao Paolo, Brazil
• ¹⁷⁴ Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY USA
• ¹⁷⁵ Bayer AG, Pharmaceuticals - Drug Discovery, Wuppertal, Germany