A systemic review of tuberculosis with HIV coinfection in children

Pediatr Radiol. 2017 Sep;47(10):1269-1276. doi: 10.1007/s00247-017-3895-9. Epub 2017 Aug 29.

Abstract

The epidemiology of tuberculosis is adversely impacted by the human immunodeficiency virus (HIV) coinfection. HIV-infected patients are more prone to opportunistic infections, most commonly tuberculosis, and the risk of death in coinfected patients is higher than in those without HIV. Due to the impaired cellular immunity and reduced immunological response in HIV-infected patients, the classic imaging features of tuberculosis usually seen in patients without HIV may present differently. The aim of this review article is to highlight the imaging features that may assist in the diagnosis of tuberculosis in patients with HIV coinfection.

Keywords: Children; Diagnosis; Diagnostic imaging; Human immunodeficiency virus; Immunity; Opportunistic infection; Tuberculosis.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • AIDS-Related Opportunistic Infections* / diagnostic imaging
  • Child
  • Coinfection* / diagnostic imaging
  • Diagnostic Imaging*
  • Humans
  • Tuberculosis* / diagnostic imaging