STAT1 Gain-of-Function and Dominant Negative STAT3 Mutations Impair IL-17 and IL-22 Immunity Associated with CMC

Affiliations

• ¹ Chair and Institute of Environmental Medicine, UNIKA-T, Technical University Munich and Helmholtz Zentrum München-German Research Center for Environmental Health, Augsburg, Germany; ZAUM, Center of Allergy and Environment, Technical University and Helmholtz Center Munich (Member of the German Center of Lung Research (DZL)), Munich, Germany.
• ² Chair and Institute of Environmental Medicine, UNIKA-T, Technical University Munich and Helmholtz Zentrum München-German Research Center for Environmental Health, Augsburg, Germany; Dr. von Hauner Children's Hospital, Ludwig Maximilian University, Munich, Germany.
• ³ Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR1163, Neckar Medical School, Paris Descartes University, Sorbonne Paris Cité, Imagine Institute, Paris, France.
• ⁴ Department of Dermatology, Eberhard Karls University Tübingen, Tübingen, Germany.
• ⁵ Dermatologikum Hamburg, Hamburg, Germany.
• ⁶ ZAUM, Center of Allergy and Environment, Technical University and Helmholtz Center Munich (Member of the German Center of Lung Research (DZL)), Munich, Germany.
• ⁷ Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany.
• ⁸ Dr. von Hauner Children's Hospital, Ludwig Maximilian University, Munich, Germany.
• ⁹ St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, New York, New York, USA.
• ¹⁰ Chair and Institute of Environmental Medicine, UNIKA-T, Technical University Munich and Helmholtz Zentrum München-German Research Center for Environmental Health, Augsburg, Germany; Dr. von Hauner Children's Hospital, Ludwig Maximilian University, Munich, Germany; CK Care, Christine Kühne Center for Allergy Research and Education, Davos, Switzerland; Hochgebirgsklinik, Davos, Switzerland.
• ¹¹ Chair and Institute of Environmental Medicine, UNIKA-T, Technical University Munich and Helmholtz Zentrum München-German Research Center for Environmental Health, Augsburg, Germany; CK Care, Christine Kühne Center for Allergy Research and Education, Davos, Switzerland; Outpatient Clinic for Environmental Diseases, Klinikum Augsburg, Germany. Electronic address: [email protected].