Debrisoquine oxidation in schizophrenic patients treated with neuroleptics

Pharmacol Res Commun. 1988 Dec;20(12):1103-4. doi: 10.1016/s0031-6989(88)80747-1.
No abstract available

MeSH terms

  • Adult
  • Aged
  • Antipsychotic Agents / pharmacology*
  • Antipsychotic Agents / therapeutic use
  • Chlorpromazine / pharmacology
  • Debrisoquin / analogs & derivatives
  • Debrisoquin / blood
  • Debrisoquin / metabolism*
  • Female
  • Humans
  • Hydroxylation
  • Isoquinolines / metabolism*
  • Male
  • Methotrimeprazine / pharmacology
  • Middle Aged
  • Oxidation-Reduction
  • Schizophrenia / drug therapy
  • Schizophrenia / metabolism*
  • Thioridazine / pharmacology

Substances

  • Antipsychotic Agents
  • Isoquinolines
  • 4-hydroxydebrisoquin
  • Methotrimeprazine
  • Thioridazine
  • Chlorpromazine
  • Debrisoquin