Risperidone

The Food and Drug Administration (FDA)-approved indications for oral risperidone (tablets, oral solution, and M-TABs) include the treatment of schizophrenia (in adults and children aged 13 and older), bipolar I acute manic or mixed episodes as monotherapy (in adults and children aged 10 and older), bipolar I acute manic or mixed episodes adjunctive with lithium or valproate (in adults), and autism-associated irritability (in children aged 5 and older). Also, the long-acting risperidone injection has been approved for the use of schizophrenia and maintenance of bipolar disorder (as monotherapy or adjunctive to valproate or lithium) in adults. There are also many varied non-FDA-approved uses for risperidone. This activity outlines the indications, mechanism of action, administration methods, significant adverse events, contraindications, and monitoring of risperidone so providers can direct patient therapy in treating conditions for which it is indicated as part of the interprofessional team.