1 The Kennedy Krieger Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USADepartment of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USASchool of Hygiene and Public Health, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USADepartment of Psychiatry, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USASchool of Nursing, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USADepartment of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USADepartment of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USA.