Copy Number Variation in Syndromic Forms of Psychiatric Illness: The Emerging Value of Clinical Genetic Testing in Psychiatry

Christian G Bouwkamp; Anneke J A Kievit; Sander Markx; Joseph I Friedman; Laura van Zutven; Rick van Minkelen; Terry Vrijenhoek; Bin Xu; Ineke Sterrenburg-van de Nieuwegiessen; Joris A Veltman; Vincenzo Bonifati; Steven A Kushner

doi:10.1176/appi.ajp.2017.16080946

Copy Number Variation in Syndromic Forms of Psychiatric Illness: The Emerging Value of Clinical Genetic Testing in Psychiatry

Am J Psychiatry. 2017 Nov 1;174(11):1036-1050. doi: 10.1176/appi.ajp.2017.16080946.

Affiliation

¹ From the Department of Psychiatry and the Department of Clinical Genetics, Erasmus University Medical Center (Erasmus MC), Rotterdam, the Netherlands; the Department of Psychiatry and the Center for Precision Neuropsychiatry, Columbia University, New York; New York State Psychiatric Institute, New York; the Departments of Psychiatry, Neuroscience, and Human Genetics, Mount Sinai School of Medicine, New York; the Clinical Neuroscience Center, Pilgrim Psychiatric Center, West Brentwood, N.Y.; the Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands; Delta Psychiatric Center, Portugaal, the Netherlands; the Department of Human Genetics, Donders Center for Neuroscience, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands; and the Department of Clinical Genetics, School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands.

PMID: 29088930
DOI: 10.1176/appi.ajp.2017.16080946

No abstract available

Keywords: Chronic Psychiatric Illness; Copy Number Variant; Diagnosis And Classification; Genetic Counseling And Mental Illness; Genetics; Syndromic Mental Illness.

Publication types

Case Reports
Multicenter Study

MeSH terms

Adult
Body Dysmorphic Disorders / complications
Body Dysmorphic Disorders / genetics*
Congenital Abnormalities / genetics*
DNA Copy Number Variations / genetics*
Female
Genetic Testing*
Humans
Intelligence Tests
Male
Mental Disorders / complications
Mental Disorders / genetics*
Middle Aged
Psychiatry / methods*
Syndrome
Young Adult