[Stent thrombosis: what's up in 2017?]

Ann Cardiol Angeiol (Paris). 2017 Dec;66(6):393-399. doi: 10.1016/j.ancard.2017.10.007. Epub 2017 Oct 31.
[Article in French]

Abstract

Stent thrombosis (ST) is still a dreadful and threatening complication of percutaneous coronary intervention (PCI) with a high risk of morbi-mortality. Nevertheless, it becomes exceptional (0.6% at 1 year and 0.15%/year later) thanks to improvement of stents and use of new P2Y12 inhibitors. Endo-coronary imaging and especially Optical Coherence Tomography (OCT) change radically its understanding with revealing quiet systematic morphologic endoluminal abnormalities (97% of the cases). OCT becomes an essential tool in practice (ESC recommendation class IIa) and allows a therapeutic strategy optimization. Its prevention is based on mechanical causes correction and a personalized adaptation of anti-platelet treatment.

Keywords: Agrégation plaquettaire; Optical coherence tomographie; Optical coherence tomography; Platelet aggregation; Stent thrombosis; Thrombose intra-stent.

MeSH terms

  • Coronary Thrombosis / diagnosis
  • Coronary Thrombosis / diagnostic imaging*
  • Coronary Thrombosis / therapy*
  • Drug-Eluting Stents / adverse effects
  • Humans
  • Percutaneous Coronary Intervention / adverse effects*
  • Predictive Value of Tests
  • Purinergic P2Y Receptor Antagonists / therapeutic use*
  • Sensitivity and Specificity
  • Stents / adverse effects*
  • Tomography, Optical Coherence* / methods
  • Treatment Outcome

Substances

  • Purinergic P2Y Receptor Antagonists