Early prosthetic joint infection due to Ureaplasma urealyticum: Benefit of 16S rRNA gene sequence analysis for diagnosis

J Microbiol Immunol Infect. 2019 Feb;52(1):167-169. doi: 10.1016/j.jmii.2017.07.017. Epub 2017 Oct 24.

Abstract

Detection of the most frequently bacteria involved in prosthetic joint infection (PJI) is usually performed by conventional cultures. We report a case of early PJI due to Ureaplasma urealyticum, diagnosed by 16S rRNA gene sequence analysis, which highlights the interest of molecular methods if fastidious bacteria are involved in PJI.

Keywords: 16S rRNA gene; Molecular diagnosis; Prosthetic joint infection; Ureaplasma urealyticum.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged, 80 and over
  • Anti-Bacterial Agents / pharmacology
  • DNA, Bacterial / genetics
  • Humans
  • Joint Prosthesis / adverse effects
  • Joint Prosthesis / microbiology*
  • Male
  • Microbial Sensitivity Tests
  • Prosthesis-Related Infections / diagnosis*
  • Prosthesis-Related Infections / microbiology*
  • RNA, Ribosomal, 16S / genetics*
  • Sequence Analysis
  • Ureaplasma Infections / diagnosis*
  • Ureaplasma urealyticum / drug effects
  • Ureaplasma urealyticum / genetics*

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • RNA, Ribosomal, 16S