Feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope for the detection of colorectal lesions

Endoscopy. 2018 Jan;50(1):63-68. doi: 10.1055/s-0043-120666. Epub 2017 Nov 13.

Abstract

Background and study aims: The adenoma detection rate (ADR) of conventional colonoscopy can still be improved. We conducted a prospective multicenter cohort study to assess the feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope, which offers a 235° view obtained from a forward-viewing and two lateral backward-viewing lenses incorporated into one image.

Patients and methods: The study was performed between November 2015 and June 2016. EWAVE colonoscopy was performed in patients with an increased risk of colorectal cancer by experienced and EWAVE-trained endoscopists (≥ 500 colonoscopies, ≥ 10 with the EWAVE system).

Results: A total of 193 patients underwent EWAVE colonoscopy. The cecal intubation rate was 97.4 %. EWAVE colonoscopy had a polyp detection rate (PDR) of 61.1 % (118 /193), ADR of 39.9 % (77 /193), and advanced ADR of 13.5 % (26 /193). No adverse events occurred.

Conclusions: EWAVE colonoscopy is feasible and safe. The ADR appears comparable to those achieved with conventional colonoscopes in similar patient populations. To further elucidate the additional benefits of wide-angle-view colonoscopes, randomized trials would be required.

Publication types

  • Clinical Trial
  • Multicenter Study

MeSH terms

  • Adenoma / diagnostic imaging*
  • Aged
  • Cecum
  • Colonic Polyps / diagnostic imaging*
  • Colonoscopes* / adverse effects
  • Colonoscopy / instrumentation*
  • Colorectal Neoplasms / diagnostic imaging*
  • Feasibility Studies
  • Female
  • Humans
  • Intubation, Gastrointestinal
  • Male
  • Middle Aged
  • Prospective Studies

Associated data

  • NTR/NTR 4536