[Primary management of endometrial carcinoma. Joint recommendations of the French society of gynecologic oncology (SFOG) and of the French college of obstetricians and gynecologists (CNGOF)]

Gynecol Obstet Fertil Senol. 2017 Dec;45(12):715-725. doi: 10.1016/j.gofs.2017.10.008. Epub 2017 Nov 11.
[Article in French]

Abstract

Objectives: The management of endometrial carcinoma is constantly evolving. The SFOG and the CNGOF decided to jointly update the previous French recommendations (Institut national du cancer 2011) and to adapt to the French practice the 2015 recommendations elaborated at the time of joint European consensus conference with the participation of the three concerned European societies (ESGO, ESTRO, ESMO).

Material and methods: A strict methodology was used. A steering committee was put together. A systematic review of the literature since 2011 has been carried out. A first draft of the recommendations has been elaborated, with emphasis on high level of evidence. An external review by users representing all the concerned discipines and all kinds of practice was completed. Three hundred and four comments were sent by 54 reviewers.

Results: The management of endometrial carcinoma requires a precise preoperative workup. A provisional estimate of the final stage is provided. This estimation impact the level of surgical staging. Surgery should use a minimal invasive approach. The final pathology is the key of the decision concerning adjuvant therapy, which involves surveillance, radiation therapy, brachytherapy, or chemotherapy.

Conclusion: The management algorithms allow a fast, state of the art based, answer to the clinical questions raised by the management of endometrial cancer. They must be used only in the setting of a multidisciplinary team at all stages of the management.

Keywords: Cancer de l’endomètre; Clinical practice guidelines; Endometrial carcinoma; Recommandations pour la pratique clinique.

Publication types

  • Practice Guideline
  • Review
  • Systematic Review

MeSH terms

  • Brachytherapy
  • Chemotherapy, Adjuvant
  • Combined Modality Therapy
  • Consensus Development Conferences as Topic
  • Endometrial Neoplasms / pathology
  • Endometrial Neoplasms / surgery
  • Endometrial Neoplasms / therapy*
  • Female
  • Humans
  • Minimally Invasive Surgical Procedures
  • Neoplasm Staging
  • Radiotherapy, Adjuvant