Combined interventional and surgical treatment of tandem middle cerebral artery embolus and internal carotid artery occlusion: case report

J Neurosurg. 2018 Sep;129(3):718-722. doi: 10.3171/2017.6.JNS162368. Epub 2017 Nov 17.

Abstract

Tandem internal carotid artery (ICA) origin occlusion and middle cerebral artery (MCA) thromboembolism is a life-threatening condition with poor neurological outcome. The authors report on a patient presenting with acute ischemic stroke from a tandem ICA and MCA occlusion with penumbra. Emergency MCA mechanical thrombectomy was performed through percutaneous cervical ICA access due to the inability to cross the cervical carotid occlusion. Emergency carotid endarterectomy to reperfuse the poorly collateralized hemisphere and repair the ICA access site was performed 2 hours after completion of tissue plasminogen activator (tPA) infusion. This case illustrates the shortest reported interval between tPA infusion and open surgical intervention for carotid revascularization, as well as the role of direct carotid artery access for mechanical thrombectomy. The authors also describe the use of a temporizing femoral artery-to-ICA shunt to maintain cerebral perfusion in the setting of ICA occlusion.

Keywords: CCA = common carotid artery; CEA = carotid endarterectomy; ICA = internal carotid artery; MCA = middle cerebral artery; NIHSS = National Institutes of Health Stroke Scale; TICI = thrombolysis in cerebral infarction; carotid endarterectomy; eICA = extracranial ICA; intracranial thrombectomy; stroke; tPA; tPA = tissue plasminogen activator; tandem occlusion; vascular disorders.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiography, Digital Subtraction
  • Brain Ischemia / surgery
  • Carotid Artery, Internal / surgery
  • Carotid Stenosis / complications*
  • Carotid Stenosis / diagnostic imaging
  • Carotid Stenosis / surgery*
  • Cerebral Revascularization / methods*
  • Computed Tomography Angiography
  • Drug Administration Schedule
  • Emergency Medical Services / methods*
  • Endarterectomy, Carotid / methods*
  • Femoral Artery / surgery
  • Humans
  • Infarction, Middle Cerebral Artery / complications*
  • Infarction, Middle Cerebral Artery / diagnostic imaging
  • Infarction, Middle Cerebral Artery / surgery*
  • Infusions, Intravenous
  • Male
  • Reoperation
  • Thrombectomy / methods*
  • Tissue Plasminogen Activator / administration & dosage*
  • Vascular Surgical Procedures

Substances

  • Tissue Plasminogen Activator