Correlation between lung perfusion blood volume and SPECT images in patients with chronic thromboembolic pulmonary hypertension by balloon pulmonary angioplasty

Hirofumi Koike; Eijun Sueyoshi; Ichiro Sakamoto; Masataka Uetani; Tomoo Nakata; Kouji Maemura

doi:10.1016/j.clinimag.2017.11.001

Correlation between lung perfusion blood volume and SPECT images in patients with chronic thromboembolic pulmonary hypertension by balloon pulmonary angioplasty

Clin Imaging. 2018 May-Jun:49:80-86. doi: 10.1016/j.clinimag.2017.11.001. Epub 2017 Nov 11.

Authors

Hirofumi Koike¹, Eijun Sueyoshi², Ichiro Sakamoto³, Masataka Uetani⁴, Tomoo Nakata⁵, Kouji Maemura⁶

Affiliations

¹ Department of Radiological Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. Electronic address: [email protected].
² Department of Radiological Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. Electronic address: [email protected].
³ Department of Radiological Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. Electronic address: [email protected].
⁴ Department of Radiological Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. Electronic address: [email protected].
⁵ Department of Cardiovascular medicine, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. Electronic address: [email protected].
⁶ Department of Cardiovascular medicine, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. Electronic address: [email protected].

PMID: 29161579
DOI: 10.1016/j.clinimag.2017.11.001

Abstract

Objectives: We evaluated the reperfusion by balloon pulmonary angioplasty (BPA) in lung PBV and SPECT images.

Methods: In total, 17 patients and 57 sessions were evaluated. Pre-BPA and post-BPA lung PBV and SPECT/CT images, based on both anatomical segments and physiologic regions (upper/middle/lower) were compared.

Results: BPA had a positive effect on most hypoperfused/unperfused segments/regions. There was generally a high rate of agreement between PBV measurements and SPECT/CT.

Conclusions: BPA shows promise as a treatment modality for CTEPH patients. SPECT/CT, and, to a lesser extent, PBV, were useful in indicating areas in need of balloon angioplasty.

Keywords: Balloon pulmonary angioplasty; Chronic thromboembolic pulmonary hypertension; Dual-energy CT; Lung PBV; Lung perfusion SPECT.

MeSH terms

Aged
Angioplasty, Balloon / methods
Blood Volume
Female
Humans
Hypertension, Pulmonary / diagnostic imaging*
Hypertension, Pulmonary / physiopathology
Lung / diagnostic imaging*
Lung / physiopathology
Male
Middle Aged
Pulmonary Embolism / diagnostic imaging*
Tomography, Emission-Computed, Single-Photon