PERV inactivation is necessary to guarantee absence of pig-to-patient PERVs transmission in xenotransplantation

Xenotransplantation. 2017 Nov;24(6). doi: 10.1111/xen.12366. Epub 2017 Nov 23.

Authors

Marc Güell¹, Dong Niu^{1

2}, Yinan Kan¹, Haydy George¹, Tao Wang¹, I-Hsiu Lee¹, Gang Wang¹, George Church³, Luhan Yang¹

Affiliations

¹ eGenesis Inc., Boston, MA, USA.
² College of Animal Sciences, Zhejiang University, Hangzhou, China.
³ Department of Genetics, Harvard Medical School, Boston, MA, USA.

PMID: 29171094
DOI: 10.1111/xen.12366

No abstract available

Keywords: pathogen transmission; porcine endogenous retroviruses.

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MeSH terms

Animals
Endogenous Retroviruses*
Heterografts
Humans
Swine
Transplantation, Heterologous*