Antifungal Drugs in Newborns and Children

Pediatr Clin North Am. 2017 Dec;64(6):1389-1402. doi: 10.1016/j.pcl.2017.08.013. Epub 2017 Oct 4.

Abstract

Invasive fungal infections are a significant cause of morbidity and mortality in infants and children. Early diagnosis is critical, and treatment with the appropriate drug and dose should be initiated promptly. Although an increasing number of studies have examined dosing of antifungals in this population, pediatric safety and efficacy data are lacking.

Keywords: Antifungal agents; Children; Immunocompromised hosts; Newborns.

Publication types

  • Review

MeSH terms

  • Antifungal Agents / adverse effects
  • Antifungal Agents / therapeutic use*
  • Child
  • Drug Dosage Calculations
  • Humans
  • Infant
  • Infant, Newborn
  • Mycoses / drug therapy*

Substances

  • Antifungal Agents