A Case of cutaneous large B-cell lymphoma during treatment of multiple sclerosis with fingolimod

Mult Scler Relat Disord. 2018 Jan:19:115-117. doi: 10.1016/j.msard.2017.11.014. Epub 2017 Nov 16.

Abstract

The authors report a case of a 69-year-old woman with multiple sclerosis treated with fingolimod for duration of over one year who subsequently developed cutaneous large B cell lymphoma. There are few reported cases of lymphoma associated with fingolimod treatment for multiple sclerosis, but rates are higher than expected in the general population. The authors hope to promote awareness of the potential risk of this medication so that more diligent disease surveillance can be performed by both prescribing practitioners of fingolimod and their patients who receive it.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Female
  • Fingolimod Hydrochloride / adverse effects*
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Lymphoma, B-Cell / chemically induced*
  • Multiple Sclerosis / drug therapy*
  • Skin Neoplasms / chemically induced*

Substances

  • Immunosuppressive Agents
  • Fingolimod Hydrochloride