Bone marrow aspirations in oncological patients: experience from an in-house standard in paediatrics

Wien Med Wochenschr. 2019 Mar;169(3-4):82-86. doi: 10.1007/s10354-017-0611-1. Epub 2017 Dec 1.

Abstract

Background: Nearly all paediatric patients require deep sedation when undergoing bone marrow aspiration (BMA). We analyzed the data from our protocols documented in a standardised procedure for bone marrow puncture over a period of 2 years.

Methods: Our standard included the documentation of personal data as well as vital parameters. In addition, we documented all medications administered, potential complications and required intervention measures, as necessary.

Results: A total of 107 protocols were available for the evaluation. Our standard covered the usage of midazolam and S‑ketamine and resulted in complications in just 9 patients, which could be remedied using simple measures. For both active substances, the dosage necessary to reach sufficient deep analgosedation was significantly higher for patients under 24 months of age.

Conclusions: Our standard for BMA provides a practical and feasible procedure. In addition to good examination conditions, our standard also helps ensure the safety of our patients.

Keywords: Analgosedation; Bone marrow aspiration; Paediatric patients; Sedation; Standard.

MeSH terms

  • Bone Marrow Examination / methods*
  • Child
  • Conscious Sedation*
  • Humans
  • Midazolam
  • Neoplasms / pathology*
  • Pain Measurement
  • Pediatrics
  • Retrospective Studies
  • Spinal Puncture / methods*

Substances

  • Midazolam