Gut Transit in Duchenne Muscular Dystrophy Is Not Impaired: A Study Utilizing Wireless Motility Capsules

Dror Kraus; Brenda Wong; Shengyong Hu; Ajay Kaul

doi:10.1016/j.jpeds.2017.10.063

Gut Transit in Duchenne Muscular Dystrophy Is Not Impaired: A Study Utilizing Wireless Motility Capsules

J Pediatr. 2018 Mar:194:238-240. doi: 10.1016/j.jpeds.2017.10.063. Epub 2017 Dec 7.

Authors

Dror Kraus¹, Brenda Wong², Shengyong Hu², Ajay Kaul³

Affiliations

¹ Department of Neurology, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel. Electronic address: [email protected].
² Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
³ Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

PMID: 29224937
DOI: 10.1016/j.jpeds.2017.10.063

Abstract

We examined gut transit in 7 young adults (18-24 years of age) with Duchenne muscular dystrophy using wireless motility capsules. Total and segmental gut transit times were normal in essentially all patients. Our study using a validated tool suggests normal transit constipation as the pathophysiologic basis for constipation in Duchenne muscular dystrophy.

Keywords: Duchenne muscular dystrophy; constipation; gastrointestinal motility; wireless motility capsule.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Capsule Endoscopy / methods*
Constipation / physiopathology*
Gastrointestinal Transit / physiology*
Humans
Male
Muscular Dystrophy, Duchenne / physiopathology*
Young Adult