Abstract
The protective effects of alpha-tocopherol, carnosine and their mixture on monooxygenase system during lipid peroxidation in liver microsome membranes were studied. It was shown that for optimal protection effect of cytochrome P-450 system the mixture of water and liposoluble antioxidants is required.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Animals
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Antioxidants / pharmacology*
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Carnosine / pharmacology
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Cytochrome P-450 Enzyme System / metabolism*
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Lipid Peroxidation / drug effects*
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Microsomes, Liver / drug effects*
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Microsomes, Liver / enzymology
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Oxygenases / metabolism
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Rats
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Rats, Inbred Strains
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Solubility
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Vitamin E / pharmacology
Substances
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Antioxidants
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Vitamin E
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Carnosine
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Cytochrome P-450 Enzyme System
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Oxygenases