Transvenous pacemaker implantation after the bidirectional Glenn operation for patients with complex congenital disease

J Cardiovasc Electrophysiol. 2018 Mar;29(3):497-503. doi: 10.1111/jce.13404. Epub 2018 Jan 5.

Abstract

Introduction: The bidirectional Glenn operation for congenital heart disease produces anatomical constraints to conventional transvenous pacemaker implantation. An iliac approach, although not previously described in this population, is potentially a preferable alternative to a thoracotomy for epicardial pacing.

Methods and results: A single-center retrospective review was performed for all patients that underwent transvenous pacemaker implantation following the bidirectional Glenn operation with partial biventricular repair. Follow-up data, implant indications, and techniques were recorded. Five patients underwent a transvenous iliac approach (median age 26.9 years, interquartile range [IQR] 25.8-27.6). Pacing indications included AV block in 3 patients (2 requiring cardiac resychronization therapy) and sinus node dysfunction in 2. Implanted leads were atrial in 4 and ventricular in 3 (1 of the latter was placed in the coronary sinus). In two cases, transvenous leads were tunneled to a preexisting epicardial abdominal generator. Median follow-up was 4.1 years (range 1.0-16.7 years). One patient underwent device revision for lead position-related groin discomfort; a second patient developed atrial lead failure following a Maze operation and underwent lead replacement by the iliac approach. Patients were not routinely anticoagulated postprocedure given lead position in the subpulmonary circulation. At last follow-up, all patients were alive. One patient underwent heart transplantation 6 months after implant with only partial resolution of pacing-induced cardiomyopathy.

Conclusions: Trans-iliac pacemaker placement may be an effective alternative to surgery for patients requiring permanent pacing after the Glenn operation.

Keywords: Glenn operation; atrioventricular block; congenital heart disease; sinus node dysfunction; transvenous pacemaker.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Arrhythmias, Cardiac / diagnosis
  • Arrhythmias, Cardiac / etiology
  • Arrhythmias, Cardiac / physiopathology
  • Arrhythmias, Cardiac / therapy*
  • Cardiac Pacing, Artificial*
  • Catheterization, Peripheral / adverse effects
  • Catheterization, Peripheral / methods*
  • Child
  • Female
  • Fontan Procedure / adverse effects*
  • Heart Defects, Congenital / surgery*
  • Heart Rate
  • Humans
  • Iliac Vein*
  • Male
  • Pacemaker, Artificial*
  • Retrospective Studies
  • Treatment Outcome