Eosinophilic fasciitis during pregnancy: case report and review of literature

Rheumatol Int. 2018 Mar;38(3):525-529. doi: 10.1007/s00296-017-3908-x. Epub 2017 Dec 15.

Abstract

The authors describe the case of a 23-year-old woman who was referred to the rheumatologist due to symmetrical and progressive stiffness, induration, and swelling of arms and thighs at the 12th week of her first gestation. The characteristic clinical aspect of 'peau d'orange', associated to the histopathologic results of the deep biopsy of the skin confirmed the diagnosis of eosinophilic fasciitis. Treatment with oral prednisone, at an initial dose of 1 mg/kg/day, was effective and rapidly tapered to 10 mg/day till the birth of a healthy newborn. A literature review showed only one previous description of pregnancy and eosinophilic fasciitis.

Keywords: Diagnosis; Eosinophilic fasciitis; Pregnancy; Treatment.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Biopsy
  • Eosinophilia* / diagnosis
  • Eosinophilia* / drug therapy
  • Fasciitis* / diagnosis
  • Fasciitis* / drug therapy
  • Female
  • Glucocorticoids / administration & dosage
  • Humans
  • Live Birth
  • Prednisone / administration & dosage
  • Pregnancy
  • Pregnancy Complications* / diagnosis
  • Pregnancy Complications* / drug therapy
  • Treatment Outcome
  • Young Adult

Substances

  • Glucocorticoids
  • Prednisone

Supplementary concepts

  • Eosinophilic Fasciitis