Symptomatic congenital Cytomegalovirus deafness: the impact of a six-week course of antiviral treatment on hearing improvement

Infez Med. 2017 Dec 1;25(4):347-350.

Abstract

Congenital Cytomegalovirus infection is the leading non-genetic cause of neurosensory deafness. We compared the outcomes of a treated group of children to an untreated group. The effect of antiviral therapy on hearing improvement between baseline and 2-year follow-up was statistically significant. These results suggest that the benefit of 6-week therapy is not limited to preventing further hearing deterioration.

MeSH terms

  • Antiviral Agents / therapeutic use*
  • Cytomegalovirus Infections / congenital
  • Cytomegalovirus Infections / drug therapy*
  • Female
  • Ganciclovir / analogs & derivatives*
  • Ganciclovir / therapeutic use*
  • Hearing Loss, Sensorineural / congenital
  • Hearing Loss, Sensorineural / drug therapy*
  • Humans
  • Infant, Newborn
  • Male
  • Retrospective Studies
  • Valganciclovir

Substances

  • Antiviral Agents
  • Valganciclovir
  • Ganciclovir