IgG4 hypophysitis - a rare and underdiagnosed cause of pituitary gland and stalk mass-like thickening

Br J Neurosurg. 2020 Feb;34(1):91-93. doi: 10.1080/02688697.2017.1416061. Epub 2018 Jan 1.

Abstract

Our aim is to present a typical case of IgG4-related hypophysitis, which will offer insight into the aetiology and pathogenesis of this relatively newly described disease. IgG4 Related Disease is a protean systemic condition that mimics inflammatory, infectious, and malignant processes. Biopsy of affected organs will show a typical histopathological pattern.

Keywords: IgG4; IgG4 related disease (IgG4-RD); IgG4-related hypophysitis; pituitary thickening.

Publication types

  • Case Reports

MeSH terms

  • Autoimmune Hypophysitis / diagnostic imaging
  • Autoimmune Hypophysitis / pathology*
  • Biopsy
  • Female
  • Humans
  • Immunoglobulin G*
  • Magnetic Resonance Imaging
  • Middle Aged
  • Pituitary Function Tests
  • Pituitary Gland / diagnostic imaging
  • Pituitary Gland / pathology*
  • Tomography, X-Ray Computed

Substances

  • Immunoglobulin G