Multifocal brain involvement in a patient with hairy cell leukemia successfully treated with rituximab and cladribine

Anamarija M Perry; Kant Matsuda; Vikram Wadhwa; Donna Hewitt; Muhamad Almiski; James B Johnston; Versha Banerji

doi:10.1182/bloodadvances.2017004697

Multifocal brain involvement in a patient with hairy cell leukemia successfully treated with rituximab and cladribine

Blood Adv. 2017 May 30;1(14):899-902. doi: 10.1182/bloodadvances.2017004697. eCollection 2017 Jun 13.

Authors

Anamarija M Perry¹, Kant Matsuda¹, Vikram Wadhwa², Donna Hewitt³, Muhamad Almiski¹, James B Johnston^{3

4}, Versha Banerji^{3

4}

Affiliations

¹ Department of Pathology and.
² Department of Radiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
³ Research Institute of Oncology and Hematology, CancerCare Manitoba, Winnipeg, MB, Canada; and.
⁴ Section of Hematology/Oncology, Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba and CancerCare Manitoba, Winnipeg, MB, Canada.

Abstract

Brain involvement, although rare, can occur in HCL.The combination of cladribine and rituximab is a highly effective treatment of HCL with brain involvement.