Reliability of morning, before-dinner, and at-bedtime home blood pressure measurements in patients with hypertension

J Clin Hypertens (Greenwich). 2018 Feb;20(2):315-323. doi: 10.1111/jch.13165. Epub 2018 Jan 6.

Abstract

The authors evaluated differences in the reliability of home blood pressure measurements taken in the morning, before dinner, and at bedtime. Forty-eight patients with hypertension (age range, 50-89 years; mean age, 76.4 years) measured their home blood pressure using a validated automatic information/communication technology-based device for 14 consecutive days. Those days were divided into the first seven days (1-7) and the following 8 to 14 days (days 8-14) and compared systolic blood pressure (SBP) reliability in the two periods for each measurement time point. In Bland-Altman analyses, morning SBP showed the least standard error of measurement (3.0 mm Hg). There were fixed biases in morning and before-dinner SBP with average limits of agreement of 3.9 and 6.4 mm Hg, respectively. For at-bedtime SBP, a random error was detected and the minimal detectable change was 13.8 mm Hg. The percentage of near-maximal variation of morning SBP was the smallest at 18.1%. Morning SBP therefore provided the most reliable home blood pressure value in the day.

Keywords: at-bedtime blood pressure; before-dinner blood pressure; morning blood pressure; reliability.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antihypertensive Agents / therapeutic use*
  • Blood Pressure / physiology*
  • Blood Pressure Monitoring, Ambulatory* / instrumentation
  • Blood Pressure Monitoring, Ambulatory* / methods
  • Circadian Rhythm / physiology
  • Electronic Data Processing
  • Female
  • Humans
  • Hypertension* / diagnosis
  • Hypertension* / drug therapy
  • Hypertension* / epidemiology
  • Hypertension* / physiopathology
  • Japan / epidemiology
  • Male
  • Middle Aged
  • Prospective Studies
  • Reproducibility of Results
  • Sphygmomanometers*
  • Time Factors

Substances

  • Antihypertensive Agents

Associated data

  • UMIN-CTR/UMIN000019871