Clinical significance of intrapancreatic choledochal cyst excision in surgical management of type I choledochal cyst

J Int Med Res. 2018 Mar;46(3):1221-1229. doi: 10.1177/0300060517728598. Epub 2018 Jan 11.

Abstract

Objective To investigate the effectiveness of intrapancreatic choledochal cyst excision in treating type I choledochal cyst, and increase understanding of the need for thorough surgical management of the disease. Methods Primary and secondary (including multiple) surgical cases, treated between 2005 and 2015, were retrospectively analysed, and follow-up data of post-treatment effectiveness to date were reviewed. Differences in curative effects were compared between whole and partial excision of the choledochal cyst. Results Out of 350 cases, patients with whole excision of the choledochal cyst ( n = 272) experienced no associated symptoms in the long-term (3/272 [1.1%] experienced stomach ache or fever). Patients with partial resection of the choledochal cyst ( n = 78) developed associated symptoms, including new cyst, calculus of the bile duct (51/78 [65.4%]), and carcinogenesis (11/78 [14.1%]) in the residual intrapancreatic biliary duct. Post-treatment clinical manifestations were significantly different between patients with partial resection versus whole excision of the choledochal cyst ( P<0.05). Conclusion Surgical re-excision should be considered in patients with a residual intrapancreatic portion of the choledochal cyst due to prior incomplete surgery, regardless of clinical symptoms.

Keywords: Type I choledochal cyst; intrapancreatic portion of the choledochal cyst; surgical management.

MeSH terms

  • Adolescent
  • Adult
  • Bile Duct Neoplasms / diagnosis*
  • Bile Duct Neoplasms / etiology
  • Bile Duct Neoplasms / pathology
  • Bile Ducts / pathology
  • Bile Ducts / surgery*
  • Calcinosis / diagnosis*
  • Calcinosis / etiology
  • Calcinosis / pathology
  • Child
  • Choledochal Cyst / pathology
  • Choledochal Cyst / surgery*
  • Cystectomy / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / diagnosis
  • Recurrence
  • Reoperation / statistics & numerical data
  • Retrospective Studies
  • Treatment Outcome