Objective: To survey the mothers' acceptance of the HPV vaccination for their adolescent girls in Xiamen and to explore the influencing factors. Methods: Mothers of adolescent girls were selected by multistage cluster random sampling. Data of demography of the mothers and girls, the knowledge and attitude of cervical cancer and HPV vaccine of the mothers were collected. The influencing factors of mothers' attitudes were analyzed with univariate and multivariate logistic regression. Results: A total of 2 307 mothers were selected. The average age of mothers was (38.0±4.7) years. 13.1% (300) of the mothers had a family history of malignant tumor. The mothers' acceptance for vaccinating girls was 61.9% (1 428). The awareness rates of HPV and HPV vaccine were 42.5% (980) and 21.4% (493), respectively. Mothers who had family history of cancer (OR=1.36, 95%CI:1.02-1.82) showed a greater willingness to vaccinate their girls than the mothers who had not. Mothers who had knowledge of HPV (OR=1.32, 95%CI:1.08-1.62) and HPV (OR=2.03, 95%CI:1.56-2.66) vaccines showed a greater willingness to vaccinate their girls than the mothers who had not. Conclusion: The mothers' acceptance to vaccinate adolescent girls against cervical cancer needs to be raised, especially for the mothers who had not family history of cancer, no-knowledge of HPV and HPV vaccines.
目的： 分析厦门市母亲接受女儿接种HPV疫苗情况及相关因素。 方法： 于2015年9月，采用多阶段整群随机抽样的方法在厦门市6个区324所小学和82所中学中抽取90个班级，将抽中班级2 700名女童的母亲作为调查对象；采用自填式问卷调查方法，收集基本情况及母亲对HPV和HPV疫苗的知晓情况等信息，有效问卷2 307份；采用多因素logistic回归模型分析母亲对女儿接种HPV疫苗的知晓和接受情况的相关因素。 结果： 2 307名调查对象的年龄为（38.0±4.7）岁，13.1%（300名）的调查对象有恶性肿瘤家族史；对女儿接种HPV疫苗的接受率为61.9%（1 428名），HPV、HPV疫苗的知晓率分别为42.5%（980名）和21.4%（493名）。多因素分析结果显示，与无恶性肿瘤家族史者相比，有恶性肿瘤家族史者愿意女儿接种HPV疫苗的OR（95%CI）值为1.36（1.02~1.82）；与不知晓HPV者相比，知晓HPV者愿意女儿接种HPV疫苗的OR（95%CI）值为1.32（1.08~1.62）；与不知晓HPV疫苗者相比，知晓HPV疫苗者愿意女儿接种HPV疫苗OR（95%CI）值为2.03（1.56~2.66）。 结论： 厦门市母亲对女儿接种HPV疫苗的接受率有待提高，尤其是无恶性肿瘤家族史、不知晓HPV及HPV疫苗者。.
Keywords: Cross-sectional studies; Papillomavirus vaccines; Vaccination.