Chronic airway inflammation,a main pathologic process of chronic obstructive pulmonary disease (COPD),can trigger inflammation cells and airway structure cells to produce bioactive molecules,which play key roles in the pathogenesis of COPD and are also an efficient indicators for the diagnosis and treatment of COPD. This article reviews the important roles of these exhaled air molecules in the diagnosis and treatment of COPD,with an attempt to offer new strategies in the management of COPD.
慢性气道炎症是慢性阻塞性肺疾病(COPD)的主要病理过程,气道炎症可导致炎症细胞及气道细胞产生具有生物活性的气体分子,其在COPD的病理进程中发挥重要作用,同时也是COPD诊断和治疗的有效判断指标。本文主要综述呼出气体分子在COPD诊断和治疗过程中的作用,旨在为COPD的防治提供新的策略。.