Prognostic factors for progression in atypical meningioma

J Neurosurg. 2018 Nov 1;129(5):1240-1248. doi: 10.3171/2017.6.JNS17120. Epub 2018 Jan 19.

Abstract

In patients with postoperative residual atypical meningiomas, by using volumetric instead of linear measurements in follow-up imaging studies, the authors detected disease progression earlier. By using this approach, treatment for recurrent disease can be instituted promptly with potentially better tumor control and less toxicity due to smaller volume of residual disease.

Keywords: CI = confidence interval; GTR = gross-total resection; Grade 2 meningioma; HR = hazard ratio; PFS = progression-free survival; PORT = postoperative RT; RT = radiation therapy; SRS = stereotactic radiosurgery; STR = subtotal resection; atypical meningioma; growth rate; oncology; postoperative radiotherapy; prognostic factors; volumetric measurement.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Disease Progression
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Meningeal Neoplasms / pathology*
  • Meningeal Neoplasms / surgery
  • Meningioma / pathology*
  • Meningioma / surgery
  • Middle Aged
  • Prognosis
  • Progression-Free Survival
  • Retrospective Studies
  • Treatment Outcome