Electroencephalographic monitoring for seizure identification and prognosis in term neonates

Shavonne L Massey; Frances E Jensen; Nicholas S Abend

doi:10.1016/j.siny.2018.01.001

Electroencephalographic monitoring for seizure identification and prognosis in term neonates

Semin Fetal Neonatal Med. 2018 Jun;23(3):168-174. doi: 10.1016/j.siny.2018.01.001. Epub 2018 Jan 17.

Authors

Shavonne L Massey¹, Frances E Jensen², Nicholas S Abend²

Affiliations

¹ Department of Neurology and Pediatrics, Children's Hospital of Philadelphia and the University of Pennsylvania, Philadelphia, PA, USA. Electronic address: [email protected].
² Department of Neurology and Pediatrics, Children's Hospital of Philadelphia and the University of Pennsylvania, Philadelphia, PA, USA.

PMID: 29352657
DOI: 10.1016/j.siny.2018.01.001

Abstract

Seizures represent a manifestation of neurological disease in the neonatal period. Historically, neonatal seizures were identified by direct clinical observation. However, since most seizures are electroencephalographic (EEG)-only (subclinical, non-convulsive) and clinical manifestations may be subtle, many clinicians place increasing importance on EEG data including conventional EEG or amplitude-integrated EEG to identify seizures in neonates. Beyond seizure identification, the EEG is a robust source of information about brain function that can be useful for neurobehavioral prognostication in some neonates. This review summarizes the available data regarding EEG for neonatal seizure diagnosis and brain function assessment.

Keywords: Electroencephalography; Neonate; Seizure; Status epilepticus.

Publication types

Review

MeSH terms

Brain / physiopathology*
Electroencephalography / methods*
Humans
Infant, Newborn
Prognosis
Seizures / diagnosis*
Seizures / physiopathology
Status Epilepticus / diagnosis*
Status Epilepticus / physiopathology