Outcomes and cost-effectiveness of ultrasound-guided injection of the trochanteric bursa

Rheumatol Int. 2018 Mar;38(3):393-401. doi: 10.1007/s00296-018-3938-z. Epub 2018 Jan 20.

Abstract

We hypothesized that ultrasound (US) guidance improves outcomes of corticosteroid injection of trochanteric bursitis. 40 patients with greater trochanteric pain syndrome defined by pain to palpation over the trochanteric bursa were randomized to injection with 5 ml of 1% lidocaine and 80 mg of methylprednisolone using (1) conventional anatomic landmark palpation guidance or (2) US guidance. Procedural pain (Visual Analogue Pain Scale), pain at outcome (2 weeks and 6 months), therapeutic duration, time-to-next intervention, and costs were determined. There were no complications in either group. Ultrasonography demonstrated that at least a 2-in (50.8 mm) needle was required to consistently reach the trochanteric bursa. Pain scores were similar at 2 weeks: US: 1.3 ± 1.9 cm; landmark: 2.2 ± 2.5 cm, 95% CI of difference: - 0.7 < 0.9 < 2.5, p = 0.14. At 6 months, US was superior: US: 3.9 ± 2.0 cm; landmark: 5.5 ± 2.6 cm, 95% CI of difference: 0.8 < 1.6 < 2.4, p = 0.036. However, therapeutic duration (US 4.7 ± 1.4 months; landmark 4.1 ± 2.9 months, 95% CI of difference - 2.2 < - 0.6 < 1.0, p = 0.48), and time-to-next intervention (US 8.7 ± 2.9 months; landmark 8.3 ± 3.8 months, 95% CI of difference - 2.8 < - 0.4 < 2.0, p = 0.62) were similar. Costs/patient/year was 43% greater with US (US $297 ± 99, landmark $207 ± 95; p = 0.017). US-guided and anatomic landmark injection of the trochanteric bursa have similar 2-week and 6-month outcomes; however, US guidance is considerably more expensive and less cost-effective. Anatomic landmark-guided injection remains the method of choice, but should be routinely performed using a sufficiently long needle [at least a 2 in (50.8 mm)]. US guidance should be reserved for extreme obesity or injection failure.

Keywords: Bursitis; Corticosteroid; Injection; Trochanteric; Ultrasound.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Anatomic Landmarks
  • Anesthetics, Local / administration & dosage*
  • Anesthetics, Local / adverse effects
  • Anesthetics, Local / economics*
  • Bursa, Synovial / diagnostic imaging
  • Bursa, Synovial / drug effects*
  • Bursa, Synovial / physiopathology
  • Bursitis / diagnostic imaging
  • Bursitis / drug therapy*
  • Bursitis / economics*
  • Bursitis / physiopathology
  • Cost-Benefit Analysis
  • Drug Costs*
  • Equipment Design
  • Female
  • Femur
  • Glucocorticoids / administration & dosage*
  • Glucocorticoids / adverse effects
  • Glucocorticoids / economics*
  • Humans
  • Injections, Intralesional
  • Lidocaine / administration & dosage*
  • Lidocaine / adverse effects
  • Lidocaine / economics*
  • Male
  • Methylprednisolone / administration & dosage*
  • Methylprednisolone / adverse effects
  • Methylprednisolone / economics*
  • Middle Aged
  • Needles / economics
  • Pain Measurement
  • Palpation / economics
  • Preliminary Data
  • Time Factors
  • Treatment Outcome
  • Ultrasonography, Interventional / adverse effects
  • Ultrasonography, Interventional / economics*
  • United States

Substances

  • Anesthetics, Local
  • Glucocorticoids
  • Lidocaine
  • Methylprednisolone