Quantifying bone structure, micro-architecture, and pathophysiology with MRI

S Singh; T J P Bray; M A Hall-Craggs

doi:10.1016/j.crad.2017.12.010

Quantifying bone structure, micro-architecture, and pathophysiology with MRI

Clin Radiol. 2018 Mar;73(3):221-230. doi: 10.1016/j.crad.2017.12.010.

Authors

S Singh¹, T J P Bray², M A Hall-Craggs³

Affiliations

¹ Centre for Medical Imaging, University College London, 3(rd) Floor East 250 Euston Road, London NW12BU, UK. Electronic address: [email protected].
² Centre for Medical Imaging, University College London, 3(rd) Floor East 250 Euston Road, London NW12BU, UK.
³ Centre for Medical Imaging, University College London, 3(rd) Floor East 250 Euston Road, London NW12BU, UK. Electronic address: [email protected].

PMID: 29361274
DOI: 10.1016/j.crad.2017.12.010

Abstract

The radiology of bone has been transformed by magnetic resonance imaging, which has the ability to interrogate bone's complex architecture and physiology. New techniques provide information about both the macrostructure and microstructure of bone ranging from micrometre detail to the whole skeleton. Furthermore functional information about bone physiology can be used to detect disease early before structural changes occur. The future of bone imaging is in quantifying the anatomical and functional information to diagnose and monitor disease more precisely. This review explores the state of the art in quantitative MRI bone imaging.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Biomechanical Phenomena
Bone Diseases / diagnostic imaging*
Bone Diseases / physiopathology*
Bone and Bones / physiopathology*
Bone and Bones / ultrastructure*
Humans
Magnetic Resonance Imaging / methods*

Abstract

Publication types

MeSH terms

Grants and funding