Early Hemodynamic Response Assessment of Stereotactic Radiosurgery for a Cerebral Arteriovenous Malformation Using 4D Flow MRI

C Q Li; A Hsiao; J Hattangadi-Gluth; J Handwerker; N Farid

doi:10.3174/ajnr.A5535

Early Hemodynamic Response Assessment of Stereotactic Radiosurgery for a Cerebral Arteriovenous Malformation Using 4D Flow MRI

AJNR Am J Neuroradiol. 2018 Apr;39(4):678-681. doi: 10.3174/ajnr.A5535. Epub 2018 Jan 25.

Authors

C Q Li¹, A Hsiao², J Hattangadi-Gluth³, J Handwerker², N Farid²

Affiliations

¹ From the Department of Radiology (C.Q.L., A.H., J.H., N.F.), University of California, San Diego, San Diego, California [email protected].
² From the Department of Radiology (C.Q.L., A.H., J.H., N.F.), University of California, San Diego, San Diego, California.
³ Department of Radiation Medicine and Applied Sciences (J.H.-G.), University of California, San Diego, La Jolla, California.

Abstract

Brain AVMs treated with stereotactic radiosurgery typically demonstrate a minimum latency period of 1-3 years between treatment and nidus obliteration. Assessment of treatment response is usually limited to evaluation of AVM nidus structural changes using conventional MR imaging and MRA techniques. This report describes the use of 4D Flow MRI to also measure radiation-induced hemodynamic changes in a Spetzler-Martin grade III AVM, which were detectable as early as 6 months after treatment.

Publication types

Case Reports

MeSH terms

Humans
Intracranial Arteriovenous Malformations / diagnostic imaging*
Intracranial Arteriovenous Malformations / surgery*
Magnetic Resonance Imaging / methods*
Male
Radiosurgery / methods
Retrospective Studies
Treatment Outcome
Young Adult