Heavy/light chain (HLC) assay will enable us to evaluate the changes in the concentrations of iHLC and uHLC separately and to better identify whether the change observed is clonal or reactive. It would therefore aid in decision making for earlier implementation or discontinuation of treatment for patients with intact immunoglobulin multiple myeloma (MM).
Keywords: Deep response; disease monitoring; involved/uninvolved HLC ratio; multiple myeloma; serum heavy/light chain (HLC) assay.