Contemporary Perspectives in Durable Mechanical Circulatory Support: What Did We Learn in the Last 3 Years?

Curr Cardiol Rep. 2018 Jan 29;20(1):6. doi: 10.1007/s11886-018-0945-3.

Abstract

Purpose of review: In this paper, we will review developments in the field of durable mechanical circulatory support over the past 3 years.

Recent findings: The role of left ventricular assist device (LVAD) placement in non-inotrope-dependent ambulatory heart failure patients remains controversial in light of recent clinical trials. New devices are on the horizon for destination therapy in advanced heart failure patients. The concept of hemocompatibility and the calculation of hemocompatibility scores represent a novel approach to common adverse events. Recent research in mechanical circulatory support has impacted our approach to durable LVAD therapy and set the stage for further advancements in the field.

Keywords: Destination therapy; Hemocompatibility; Left ventricular assist device; Mechanical circulatory support.

Publication types

  • Review

MeSH terms

  • Disease Progression
  • Heart Failure / diagnosis
  • Heart Failure / physiopathology
  • Heart Failure / therapy*
  • Heart Transplantation
  • Heart-Assist Devices / trends*
  • Humans
  • Patient Selection
  • Prosthesis Design
  • Randomized Controlled Trials as Topic
  • Risk Assessment
  • Time Factors
  • Treatment Outcome