Anaphylaxis in a food allergy outpatient department: one-year review

Eur Ann Allergy Clin Immunol. 2018 Mar;50(2):81-88. doi: 10.23822/EurAnnACI.1764-1489.45. Epub 2017 Nov 30.

Abstract

Background. Anaphylaxis is an acute, potentially fatal, multi-organ allergic reac-tion. Our aim was to characterize the population with food induced anaphylaxis followed over a one-year period. Methods. Retrospective analysis of clinical files of patients with food anaphylaxis observed in our food allergy consultation during 2016. Results. Sixty-two patients were included. In the pediatric group, the implicated allergens were cow's milk, egg and fish and in the adults' group, the commonest allergens were nuts and wheat. Allergy to shrimp affected equally children and adults. The most frequent symptoms were urticaria (85.5%), angioedema (64.5%) and dyspnea (62.9%). Cofactors were present in 32.6% of patients, mainly exercise. Asthma and/or rhinitis were the most frequent comorbidities. Conclusion. In accordance to other studies, milk and egg were the most implicated allergens in children. Anaphylaxis in adults reflects the Mediterranean sensitization pattern. Exercise was the most relevant cofactor.

Keywords: adults; anaphylaxis; cofactors; food allergy; pediatric.

MeSH terms

  • Adult
  • Anaphylaxis / diagnosis
  • Anaphylaxis / epidemiology*
  • Angioedema / diagnosis
  • Angioedema / epidemiology*
  • Child
  • Child, Preschool
  • Dyspnea / diagnosis
  • Dyspnea / epidemiology*
  • Egg Hypersensitivity / diagnosis
  • Egg Hypersensitivity / epidemiology
  • Exercise
  • Female
  • Food Hypersensitivity / diagnosis
  • Food Hypersensitivity / epidemiology*
  • Humans
  • Male
  • Milk Hypersensitivity / diagnosis
  • Milk Hypersensitivity / epidemiology
  • Nut Hypersensitivity / diagnosis
  • Nut Hypersensitivity / epidemiology
  • Retrospective Studies
  • Urticaria / diagnosis
  • Urticaria / epidemiology*
  • Wheat Hypersensitivity / diagnosis
  • Wheat Hypersensitivity / epidemiology