Pulmonary Comorbidity in Lung Cancer

Trends Mol Med. 2018 Mar;24(3):239-241. doi: 10.1016/j.molmed.2018.01.005. Epub 2018 Feb 1.

Abstract

Pulmonary hypertension (PH) is caused by many disorders that affect the pulmonary vasculature. A recent study has provided evidence that pulmonary vascular remodeling and PH can be observed in lung cancer, and this may be associated with tumor cell-immune cell inflammatory crosstalk. These findings highlight the pressing need to understand better and manage pulmonary vascular comorbidities in lung cancer.

Keywords: cardio-oncology; disease comorbidity; inflammatory; lung cancer; pulmonary hypertension.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Animals
  • Comorbidity
  • Hypertension, Pulmonary*
  • Lung Neoplasms
  • Lung*
  • Mice
  • Mice, Inbred C57BL