The HLA-A*30:02~C*18:02~B*57:03 African haplotype identified with the deletion of the HLA-DRB1 gene in individuals from La Réunion Island

HLA. 2018 Apr;91(4):289-291. doi: 10.1111/tan.13231. Epub 2018 Mar 6.

Abstract

We found a haplotype with the deletion of the HLA-DRB1 gene in two unrelated individuals originated from La Reunion Island, probably resulting from a deletion in the African haplotype A*30:02~C*18:02~B*57:03~DRB1*13:01.

Keywords: B*57:03; Bantu; DRB1; La Réunion Island; deletion; haplotype.

MeSH terms

  • Alleles
  • Black People / genetics*
  • Female
  • Gene Deletion*
  • Gene Frequency
  • HLA-A Antigens / genetics*
  • HLA-B Antigens / genetics*
  • HLA-DRB1 Chains / genetics*
  • Haplotypes / genetics*
  • Humans
  • Reunion

Substances

  • HLA-A Antigens
  • HLA-B Antigens
  • HLA-DRB1 Chains