Multiple lobar intracerebral hemorrhage and cerebral amyloid angiopathy in the setting of ApoE Є2: a case report of the disease course and call for improved treatment modalities

Patrick Thornley; Stephan Oreskovich; John Provias; Jamie Silva; Kesava Reddy; Aleksa Cenic

doi:10.1093/jscr/rjx208

Multiple lobar intracerebral hemorrhage and cerebral amyloid angiopathy in the setting of ApoE Є2: a case report of the disease course and call for improved treatment modalities

J Surg Case Rep. 2017 Oct 20;2017(10):rjx208. doi: 10.1093/jscr/rjx208. eCollection 2017 Oct.

Authors

Patrick Thornley¹, Stephan Oreskovich¹, John Provias¹, Jamie Silva¹, Kesava Reddy¹, Aleksa Cenic¹

Affiliation

¹ Division of Neurosurgery, Department of Neuropathology and Neurology, McMaster University, Hamilton, Ontario, Canada.

Abstract

We describe a case of multiple cerebral amyloid angiopathy-associated intracerebral hemorrhages (ICH) occurring at multi-focal lobar sites of the brain. A review and discussion of the current literature on the importance of Apolipoprotein E (ApoE) genotyping in prediction of ICH outcome and recurrence follows.

Publication types

Case Reports