Simplified Bernoulli formula to predict flow limiting stenosis at coronary computed tomography angiography

Clin Imaging. 2018 Sep-Oct:51:104-110. doi: 10.1016/j.clinimag.2018.01.018. Epub 2018 Feb 6.

Abstract

Objective: To compare the diagnostic performance of estimated energy loss (EEL) with diameter stenosis (DS) to estimate significant stenosis by fractional flow reserve (FFR).

Materials and methods: One hundred twenty-five patients were included. EEL was calculated using DS, lesion length, minimal lumen area and left ventricular volume. FFR ≤ 0.80 was determined significant.

Results: EEL improved the accuracy from 63% (95% confidence interval (CI): 55-72%) to 83% (95% CI: 75-89%, p < 0.0001). EEL increased the area under the receiver operating characteristics curve from 0.63 to 0.85 (p < 0.0001).

Conclusions: EEL improved the diagnostic performance to detect functionally significant stenosis than DS.

Keywords: Coronary computed tomography angiography; Fractional flow reserve; Ischemia; Simplified Bernoulli formula.

MeSH terms

  • Aged
  • Computed Tomography Angiography / methods*
  • Coronary Angiography / methods*
  • Coronary Stenosis / diagnosis*
  • Coronary Stenosis / physiopathology
  • Female
  • Fractional Flow Reserve, Myocardial / physiology*
  • Humans
  • Male
  • Multidetector Computed Tomography / methods*
  • ROC Curve
  • Severity of Illness Index