In vivo thrombin generation and subsequent APC formation are increased in factor V Leiden carriers

Blood. 2018 Mar 29;131(13):1489-1492. doi: 10.1182/blood-2017-12-823831. Epub 2018 Feb 21.
No abstract available

Publication types

  • Clinical Trial
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Factor V / genetics
  • Factor V / metabolism*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Protein C / genetics
  • Protein C / metabolism*
  • Thrombin / genetics
  • Thrombin / metabolism*
  • Venous Thromboembolism / blood*
  • Venous Thromboembolism / genetics
  • Venous Thromboembolism / pathology

Substances

  • Protein C
  • factor V Leiden
  • Factor V
  • Thrombin