Abstract
Yeast Aim21 is recruited by the SH3-containing proteins Bbc1 and Abp1 to patches and, with Tda2, reduces barbed end assembly to balance the distribution of actin between patches and cables. Aim21/Tda2 also interacts with Cap1/Cap2, revealing a complex interplay between actin assembly regulators.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Actin Capping Proteins / genetics
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Actin Capping Proteins / metabolism
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Actin Cytoskeleton / metabolism*
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Actins / metabolism*
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Cytoskeletal Proteins / genetics
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Cytoskeletal Proteins / metabolism
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Endocytosis*
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Genotype
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Microfilament Proteins / genetics
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Microfilament Proteins / metabolism*
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Microscopy, Fluorescence
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Models, Molecular
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Mutation
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Protein Binding
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Protein Conformation
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Saccharomyces cerevisiae / genetics
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Saccharomyces cerevisiae / metabolism*
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Saccharomyces cerevisiae Proteins / genetics
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Saccharomyces cerevisiae Proteins / metabolism*
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Signal Transduction
Substances
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ABP1 protein, S cerevisiae
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Actin Capping Proteins
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Actins
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BBC1 protein, S cerevisiae
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CAP1 protein, S cerevisiae
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Cap2 protein, S cerevisiae
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Cytoskeletal Proteins
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Microfilament Proteins
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Saccharomyces cerevisiae Proteins