Pharmacological inhibition of caspase-8 suppresses inflammation-induced lymphangiogenesis and allograft rejection in the cornea

J Allergy Clin Immunol. 2018 Jul;142(1):290-294.e9. doi: 10.1016/j.jaci.2018.02.005. Epub 2018 Mar 2.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Caspase 8 / immunology*
  • Caspase Inhibitors / pharmacology*
  • Corneal Transplantation*
  • Graft Rejection / enzymology*
  • Graft Rejection / immunology
  • Inflammation / enzymology
  • Inflammation / immunology
  • Lymphangiogenesis / drug effects*
  • Lymphangiogenesis / immunology
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Signal Transduction / drug effects
  • Signal Transduction / immunology

Substances

  • Caspase Inhibitors
  • Caspase 8