A new role for a tumor-suppressing protein

Elife. 2018 Mar 1:7:e35111. doi: 10.7554/eLife.35111.

Abstract

In addition to its role in preventing tumors, the protein p53 appears to participate in a DNA repair process known as the replication-stress response.

Keywords: DNA replication; cancer; chromosomes; genes; genome instability; human; mouse; p53; replication fork; replication stress response.

Publication types

  • Comment

MeSH terms

  • DNA Replication
  • Genomic Instability
  • Homeostasis
  • Humans
  • Mutagens
  • Neoplasms*
  • Rad52 DNA Repair and Recombination Protein
  • Tumor Suppressor Protein p53*

Substances

  • Mutagens
  • RAD52 protein, human
  • Rad52 DNA Repair and Recombination Protein
  • Tumor Suppressor Protein p53