The role of obesity in the risk of gestational diabetes among immigrant and U.S.-born women in New York City

Ann Epidemiol. 2018 Apr;28(4):242-248. doi: 10.1016/j.annepidem.2018.02.006. Epub 2018 Feb 15.

Abstract

Purpose: To examine if the role of obesity in the risk of gestational diabetes differs between immigrant and U.S.-born women.

Methods: We used New York City-linked 2010-2014 birth certificate and hospital data. We created four racial/ethnic groups (non-Hispanic black, Hispanic, non-Hispanic white, and Asian) and three subgroups (Mexican, Indian, and Chinese). Gestational diabetes mellitus (GDM) was ascertained by the birth certificate checkbox and discharge ICD-9 codes. We calculated relative risks for immigrant status and body mass index with GDM using covariate-adjusted log-binomial regression. We calculated multivariable population attributable risk to estimate the proportion of GDM that could be eliminated if overweight/obesity were eliminated by immigrant status.

Results: Immigrant women had higher risk of GDM than U.S.-born women, with adjusted relative risks ranging from 1.2 among non-Hispanic black women (95% confidence interval, 1.2-1.3) to 1.6 among Hispanic women (95% confidence interval, 1.4-1.8). Increasing body mass index was associated with GDM risk in all groups, but relative risks were weaker among immigrants (P for interaction <.05). The population attributable risk for overweight/obesity was lower in immigrant women than in U.S.-born women in all racial/ethnic groups.

Conclusions: The lower proportion of GDM attributable to overweight/obesity among immigrant women may point to early life and migration influences on risk of GDM.

Keywords: Disparities; Ethnicity; Gestational diabetes; Immigrant; Life course; Obesity.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Asian People / statistics & numerical data
  • Black People / statistics & numerical data
  • Black or African American
  • Body Mass Index
  • Diabetes, Gestational / epidemiology
  • Diabetes, Gestational / ethnology*
  • Diabetes, Gestational / etiology*
  • Emigrants and Immigrants / statistics & numerical data*
  • Ethnicity / statistics & numerical data*
  • Female
  • Hispanic or Latino / statistics & numerical data
  • Humans
  • New York City / epidemiology
  • Obesity / complications*
  • Overweight / complications*
  • Overweight / epidemiology*
  • Pregnancy
  • Prevalence
  • Racial Groups / statistics & numerical data*
  • Risk Factors
  • White People / statistics & numerical data
  • Young Adult