Adipose Dendritic Cells Come Out of Hiding

Nelson M LaMarche; Lydia Lynch

doi:10.1016/j.cmet.2018.02.014

Adipose Dendritic Cells Come Out of Hiding

Cell Metab. 2018 Mar 6;27(3):485-486. doi: 10.1016/j.cmet.2018.02.014.

Authors

Nelson M LaMarche¹, Lydia Lynch²

Affiliations

¹ Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
² Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland. Electronic address: [email protected].

PMID: 29514060
DOI: 10.1016/j.cmet.2018.02.014

Abstract

In this issue of Cell Metabolism, Macdougall et al. (2018) identify two subsets of conventional dendritic cells in visceral adipose tissue and demonstrate that these subsets engage distinct adipocyte-associated signaling pathways to drive their tolerogenic phenotypes in the lean state.

Publication types

Comment

MeSH terms

Adipocytes*
Dendrites
Dendritic Cells
Homeostasis
Intra-Abdominal Fat*

Grants and funding

MR/L002345/1/MRC_/Medical Research Council/United Kingdom