Bone: Bone marrow adipocytes in 3D

Nat Rev Endocrinol. 2018 May;14(5):254-255. doi: 10.1038/nrendo.2018.31. Epub 2018 Mar 16.

Abstract

Culturing bone marrow stromal cells on 3D silk scaffolds supports their proliferation and adipogenesis, while minimizing the activation of inflammatory pathways. Therefore, differentiation of bone marrow adipocytes in 3D culture might provide a more representative model for the study of bone marrow adipose tissue than is offered by traditional 2D cell cultures.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Adipocytes*
  • Adipose Tissue
  • Bone Marrow*
  • Bone and Bones
  • Humans