RETINAL MICROSTRUCTURE IN POEMS SYNDROME

Retin Cases Brief Rep. 2021 Jan 1;15(1):71-76. doi: 10.1097/ICB.0000000000000735.

Abstract

Purpose: To report a 67-year-old woman with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome, showing bilateral serous retinal detachment. The retinal lesion was evaluated by multimodal imaging using spectral domain optical coherence tomography and an adaptive optics (AO) camera.

Methods: A case report.

Results: Optical coherence tomography showed hyperreflective foci mainly in the inner retina in both eyes. The AO images showed many low-reflective dots in the right eye. Three months after hematological treatment, both hyperreflective foci in the optical coherence tomography images and the low-reflective dots in the AO images disappeared.

Conclusion: Low-reflective dots were detected in AO images of eyes with serous retinal detachment secondary to POEMS syndrome. AO cameras can detect retinal microstructures in living eyes.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Equipment Design
  • Female
  • Humans
  • Multimodal Imaging*
  • Optics and Photonics*
  • POEMS Syndrome / complications
  • POEMS Syndrome / diagnosis*
  • Retina / pathology*
  • Retinal Detachment / diagnosis*
  • Retinal Detachment / etiology
  • Tomography, Optical Coherence / methods*