[Atopic keratoconjunctivitis: One allergy may mask another. A clinical observation with two types of hypersensitivity reactions: IgE-mediated and non-IgE-mediated]

J Fr Ophtalmol. 2018 Mar;41(3):224-230. doi: 10.1016/j.jfo.2017.10.003. Epub 2018 Mar 19.
[Article in French]

Abstract

Allergies are frequently implicated in ophthalmologic practice. These typically benign allergies can be potentially severe for the ocular surface and have an impact in everyday life. We relate, through a case of keratoconjunctivitis involving 2 types of hypersensitivity, the various triggers and therapeutic choices to allow a more effective treatment.

Keywords: Atopic keratoconjunctivitis; Blepharitis; Blépharite; Conjunctival allergen provocation test; Eczema; Eczéma; Hypersensibilité médiée par les IgE (de type I); Hypersensibilité non médiée par les IgE (de type IV); IgE mediated hypersensitivity (type I); Kératoconjonctivite atopique; Non IgE mediated hypersensitivity (type IV); Test de provocation conjonctival allergénique.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Allergens / adverse effects
  • Allergens / immunology
  • Animals
  • Azithromycin / therapeutic use
  • Blepharitis / etiology
  • Blepharitis / immunology
  • Cats
  • Dermatitis, Atopic / complications
  • Desensitization, Immunologic
  • Dogs
  • Drug Therapy, Combination
  • Eosinophilia / etiology
  • Histamine Antagonists / therapeutic use
  • Humans
  • Hypersensitivity, Immediate / etiology*
  • Hypersensitivity, Immediate / immunology
  • Hypersensitivity, Immediate / therapy
  • Immunoglobulin E / immunology*
  • Intradermal Tests
  • Keratoconjunctivitis / diagnosis
  • Keratoconjunctivitis / drug therapy
  • Keratoconjunctivitis / etiology*
  • Keratoconjunctivitis / immunology
  • Lubricant Eye Drops / therapeutic use
  • Male
  • Pyroglyphidae
  • Rhinitis, Allergic, Seasonal / complications
  • Tacrolimus / therapeutic use

Substances

  • Allergens
  • Histamine Antagonists
  • Lubricant Eye Drops
  • Immunoglobulin E
  • Azithromycin
  • Tacrolimus